CRYPTIC DIVERSITY IN INDO-PACIFIC CORAL-REEF FISHES REVEALED BY DNA-BARCODING PROVIDES NEW SUPPORT TO THE CENTRE-OF-OVERLAP HYPOTHESIS.

Cryptic diversity in Indo-Pacific coral-reef fishes revealed by DNA-barcoding provides new support to the centre-of-overlap hypothesis.

Diversity in coral reef fishes is not evenly distributed and tends to accumulate in the Indo-Malay-Philippines Archipelago (IMPA).The comprehension of the mechanisms that initiated this pattern is in its infancy despite its importance for the conservation of coral reefs.Considering the IMPA either as an area of overlap or a cradle of marine biodive

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Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations.

Forward genetics screens with N-ethyl-N-nitrosourea (ENU) provide a powerful way to illuminate gene function and generate mouse models of human disease; however, the identification of causative mutations remains a limiting step.Current strategies depend on Health conventional mapping, so the propagation of affected mice requires non-lethal screens;

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